Contacts

Project Details

 

Partner 1 Umeå University, Umeå, Sweden

 

One of the largest Swedish universities, the University of Umeå, is associated with Norrland’s University Hospital, the most important center for healthcare and medical research in the North of Sweden. Umeå University was listed among the 100 best in Europe in 2011 according to the Times Higher Education magazine. This university identifies biomedical science as one of its prioritized areas of research and has a broad network of internal, national, and international collaboration. Two groups with different backgrounds and belonging to different departments will represent Umeå University in this project.

 rzhepishevska

Project Coordinator Olena Rzhepishevska

Olena Rzhepishevska is a researcher at the Department of Clinical Microbiology and a senior research engineer at the Department of Chemistry, Umeå University. Olena was born in Odessa, Ukraine and obtained her PhD in molecular biology at Umeå University, Umeå Sweden. Olena’s research interests are metabolism and metabolic signatures of infection, antibacterial compounds and surfaces, host-pathogen interaction. Olena is fluent in English, Swedish, Russian and Ukrainian, which helps her in communication with different partners.

more...

Principal research engineer
Department of Clinical Microbiology and Department of Chemistry
Umeå universitet
SE-901 87 Umeå
Sweden
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
Phone:+46 90 786 54 67

 

anders

Responsibl researcher
Anders Sjöstedt

 
 
Head of the Unit.
Department of Clinical Microbiology
Umeå University
SE-90187 Umeå 
Sweden 
Email:  This email address is being protected from spambots. You need JavaScript enabled to view it.
Phone:+46 90 785 11 20 

henrik

Group leader
Henrik Antti

Since 2004 the group of Henrik Antti at Umeå University have been working with development of methods for metabolomics and chemometric bioinformatics concerning data processing and analysis of mass spectrometry based metabolomics data.

more...

Furthermore they have applied the developed methodology to target relevant questions within health and disease. This include the study of human exercise and nutritional effects in relation to health and disease and detection of metabolic marker patterns in CSF for amyotrophic lateral sclerosis (ALS) and subtypes of the disease. Recently the methodology was applied for the discovery of metabolic markers for development of prostate cancer (PCa) bone metastases. Furthermore, in a unique study in patients of response to radiation treatment in irresectible glioblastoma brain tumors multivariate correlations were obtained between the GC/MS metabolic profiles in tumor extracellular fluid, sampled by microdialysis, and treatment response9. For this Antti and co-workers have developed protocols for metabolite extraction and analysis in a variety of mammalian biofluids and tissues, including blood (plasma, serum, and erythrocytes), urine, cerebrospinal fluid, saliva, microdialysis fluid as well as tumor, bone and fatty tissue. A recent interest is to apply the methodology for the study of infectious diseases. In this area Antti and co-workers have studied the potential of metabolomics for efficient and specific diagnosis of bacterial infections and antibiotic resistance patterns with positive results (unpublished). In collaboration with Professor Stephen Baker, OUCRU, Ho Chi Min City, Vietnam, the group has recently initiated a project where the methodology is be applied on clinical samples from humans in areas endemic for typhoid fever with the aim of finding metabolic markers of acute infection, identification of chronic carriers and antibiotic resistance. Our ambition is now to extend the application of the methodology to include samples from tuberculosis patients. In this we envisage that methodology and knowledge will be translated from the other projects running, especially in the area of infectious disease.


Senior lecturer
Department of Chemistry
Umeå universitet
SE-901 87 Umeå
Sweden
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
Phone: +46 90 786 53 59

 

Partner 2 - Odessa National University, Odessa, Ukraine

 

Odessa National University is one of the leading Ukrainian universities with a longstanding history of biological and microbiological studies. The Department of Microbiology and Virology is well equipped and its research is focused on plant and human pathogens, marine ecology and biotechnology. Due to the teaching activity at the Dept. of Microbiology and Virology, about 20 Master of Science graduate yearly, with knowledge and skills that make them attractive employees for clinical and research labs. ONU has also a Biotech Center with the necessary facilities to support up-to-date biomedical research. ONU is officially nominated as FP7 NCP in FAFB (Agriculture and Fisheries, and Biotechnology) and has participated in such research and educational projects like inter alia FP6 and FP7 projects, TEMPUS, TASIS, INTAS and Erasmus Mundus. ONU has wide experience in international cooperation and signed bilateral agreements with more than 100 universities from Europe and other parts of the world.

filipova

Responsible researcher
Tetiana O. Filipova
(Russian spelling “Filippova”)

Tetiana O. Filipova holds PhD in Pharmacology, DSc in Pharmacology, professor at the Department of Microbiology and Virology.

more...

The group of Tetiana Filipova has produced over 150 scientific papers and reports. The research interests in our group are: pharmacology, immunopharmacology, novel antimicrobial drugs, interaction of bacteriophages with immune system, quorum sensing and biofilm control.

 

2  Shampanskiy pereulok,  aud. 32, 
Biological faculty
Department of Microbiology, Virology and Biotechnology
Odessa, Ukraine, 
65058
Email
Phone: +380 048  68-79-64 

 

stepanova

Stepanova Tatyana
Researcher
Stepanova Tatyana: researcher, microbiologist and immunologist.

more...

For several years has worked at Odessa National University as a representative of National Information Centre for Ukraine-EU S&T Cooperation, regional expert of EU funded project JSO-ERA (Joint Support Office for Enhancing Ukraine’s Integration into the European Research Area), the coordinator of FP7 NCP for FAFB (Agriculture and Fisheries, and Biotechnology). Tatyana has knowledge and practical skills on project and grant management on FP7 and other collaborative international projects (INTAS, TASIS, and TEMPUS). Familiar with FP7 and other EU funding programmes. Microbiologist with knowledge and practical experience in a range of microbiological and pharmacological subjects and techniques gained through both academic study and work experience; experienced in experimental planning, execution and reporting.


2 Shampanskiy pereulok, aud. 32,
Biological faculty
Department of Microbiology, Virology and Biotechnology
Odessa, Ukraine,
65058
Email
Phone: +380 048 68-79-64

zinchenko

Oksana Zinchenko
Assistant professor at Microbiology and Virology Department

Oksana Zinchenko: PhD in microbiology and occupies a position of assistant professor at Microbiology and Virology Department at Odessa National University.

more...

Oksana works in collaboration with a group of organic chemists and her main scientific interest is screening of antimicrobial compounds. The main objects of her studies as a postgraduate student were synthetic analogues of natural pigments – porphyrins – and their metal-complexes. Currently, Oksana investigates the antimicrobial, antifungal and antiviral activity of nicotinic and isonicotinic acids derivatives. One of the well-known representatives of this group is isonicotinic acid hydrazide – one of the main medicines used for tuberculosis treatment. Modified molecules of isonicotinic acids, also called hydrazones, are studied as well as their complexes with p-metals. Antimicrobial and antiviral activity has been shown to increase for metal-complexes of these compounds.

 

2  Shampanskiy pereulok,  aud. 32, 
Biological faculty
Department of Microbiology, Virology and Biotechnology
Odessa, Ukraine, 
65058
Email:
Phone: +380 048  68-79-64 

afonin

Head of the Laboratory IT&TST
Sergey Afonin

Laboratory Information Technology and technical support training of biological faculty of the Odessa National University. IT support for teaching and research. The introduction of information technologies in the educational process and scientific research.

more...

 
2  Shampanskiy pereulok,  aud. 83, 
Biological faculty, Odessa, Ukraine, 
65058
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
Phone +380 048  68-16-13 

 

Partner 3 - TB Clinic, Odessa, Ukraine

 

The Regional Clinic for TB (RCTB) is one of the biggest centers dedicated to TB healthcare and diagnostics in the South of Ukraine. It has 5 departments including surgery and children department and the staff of 400 people with 26 of those employees working in a diagnostics lab. The clinical diagnostics lab (CDL) is a certified P3 facility armed with modern lab equipment thanks to funding from USAID and has a function of a reference lab for the region. CDL performs a significant amount of investigations of the samples from the patients of RCTB itself and TB clinics of the city and region with an average of 40 000 patients per year. Bacteriology Division of CDL is focused on medical microbiology and epidemiology. In 2011, 169 246 tests on pathological samples were carried out including general clinical, hematological and biochemical analysis. Among those, there were 16879 culture tests to detect M.tuberculosis and 2487 antibiotics resistance tests of M.tuberculosis.The number of studies has also increased due to the introduction to the automated Mycobacterial detection system Bactec MGIT 960 (BD).

CDL performs inter-laboratory quality control of AFB (acid fast bacilli) smear tests and quality control of diagnostics of TB based on clinical and biochemical tests. Training in TB diagnostics for new personnel is carried out with final “blind” examination. CDL conducts supervisory visit to the laboratory of the city and region.

CDL is also involved in scientific research. For example, in 2010, they carried out a survey of a group of HIV positive TB patients that allowed obtaining a detail picture of their clinical and behavioral profiles.

 

filuk

Responsible researcher Vitalij Filuk

 

 

 

Vitalij Filuk, MD, the head of the hospital, a member of the interregional working group on control and prevention of TB, HIV and drug abuse, Honored Medical Doctor of Ukraine.

rogach

Deputy chief of medical work of Odessa Regional TB Hospital

 

no fm

Dr. Valentina Stokich

 

 

 

Dr. Valentina Stokich in charge of experimental part the current project are highly experienced researchers of CDL.

no fm

Dr. Elena Nikolayevskaya

 

 

 

Dr. Elena Nikolayevskaya in charge of experimental part the current project are highly experienced researchers of CDL.

 

Partner 4 - Hospital University Germans Trias i Pujol, Badalona, Spain

 

This is a university hospital that covers a population of 200,000 inhabitants, and that acts as reference center for 800,000 inhabitants. The Microbiology Department is a reference center of the area. The research of the hospital is coordinated by the Institut Germans Trias I Pujol. The Centre is considered between the six first centres of Catalonia attending to their quality and quantity of research production. The Institute is the second of Spain in number of citations by article.

 

prat

Responsible researcher Cristina Prat

Cristina Prat is MD, PhD, specialist in clinical Microbiology and responsible for the section of respiratory tract infection and Mycobacteria of Hospital Universitari Germans Trias I Pujol.

more...

Department of Microbiology
Hospital Universitari Germans Trias i Pujol
08916 Badalona (Barcelona)
Spain
Email:
Phone:

 

dominguez

Senior scientistJose Dominguez

Jose Dominguez is MSc, PhD and senior scientist in the Institut d'Investigació Germans Trias i Pujol. His research is focused in the development and evaluation of new methods in the diagnosis and management of the respiratory infectious diseases.

more...

Department of Microbiology
Hospital Universitari Germans Trias i Pujol
08916 Badalona (Barcelona)
Spain
Email:
Phone:

molina

PhD studen Barbara Molina Moya
Department of Microbiology
Hospital Universitari Germans Trias i Pujol
08916 Badalona (Barcelona)
Spain
Email:  This email address is being protected from spambots. You need JavaScript enabled to view it.
Phone: +34 4978426

 

The Department of Microbiology has large experience in conventional techniques for the diagnosis of mycobacterial infections, receiving samples for mycobacterial studies from the hospital, from a specialized TB center from the Public Health Department, and from two penitentiary centers. It is also the reference center for tuberculosis of Catalonia (7 million inhabitants), receiving strains from other centers when necessary and specially for molecular typing. Blood samples are also received from the Unit for Prevention and Control of Tuberculosis of Barcelona and other centers for interferon gamma release assays (IGRA).

more...

Over the last 10 years, the Research Team has succeeded in building a multidisciplinary group that has been working in research related to respiratory tract infections, and especially in tuberculosis. The group is involved in several research projects and is member of a Thematic Network of Cooperative Research call at the Carlos III Health Institute. Cristina Prat belongs to the educational commission of this network. The team of the Department of Microbiology is also affiliated to the Tuberculosis Network European Trials Group (TBNET) and Dr. Jose Domínguez is a member of the steering committee in charge of microbiology and drug resistance.

The group has contributed to the enhancement of the conventional tuberculosis diagnostic techniques and of genetic amplification techniques. In the last years the research lines have derived from the real need of new and alternative methods for the diagnosis of active and latent tuberculosis infection; the rapid detection of multi-drug resistant strains of M.tuberculosis and their molecular epidemiology control; and also the host-pathogen interaction. In general, research objectives can be grouped into the following areas:

- Rapid diagnosis of active tuberculosis and new molecular methods for drug susceptibility testing of M. tuberculosis

The group has participated in the development and evaluation of new methods for detection of resistance to first and second line drugs (PCR-hibridization as well as pyrosequencing). This research line is further explored in collaboration with other groups of the above mentioned CIBERES network. We have also collaborated in in vitro studies of newly developed drugs.

Molecular typing

As a reference laboratory, the group has large experience in molecular typing of the strains by the conventional methods Restriction Fragment Length Polymorphism (RFLP) and spoligotyping for epidemiological studies. From a research point of view, we participate in projects of CIBERES together with other reference groups of Spain.

 
Saturday the 21st.